Haplotypes of SNPs associated with COX-2 and their comparison with histopathological features of breast cancer patients
نویسندگان
چکیده
Methods We selected 150 HER-2 amplification positive breast cancer patients from our previous case-control study. The participants were evaluated for histopathological features and genotyped for COX-2 SNPs. Comparisons of genotype data with histopathological characteristics were performed by chi square test. Logistic regression was applied for estimation of odd ratios. COX-2 protein level and other markers were assessed by immunohistochemical staining. Statistical analyses were performed using SPSS version 19.0 and p value was set at <0.05.
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